The city is situated in Andhra Pradesh between some of the prime hotspot locations; Hyderabad, Bangalore Highway and Railway line. It is situated at 14.68°N 77.6°E and is elevated at height of 335 meters (1099 feet).
The city experiences semi-arid climate, and also witnesses hot and dry conditions for most part of the year. Summers commence in late February and the temperature is highest in the month of May and reaches up to 37 °C (99 °F) range. The city receives pre-monsoon showers in early March and monsoon in September till November. Winter season starts from late November and ends in early February.
It is not difficult to reach various major cities in the country from Anantapuram City as the city is well-connected by NH7 and NH 205. The city also boasts its direct train connection that makes possible for the passengers to easily reach regions like Vishakapatnam, Hyderabad, Pune, Bangalore, Bhubaneswar, Mumbai, Jaipur etc. The nearest airport to the city is Puttaparthi and is precisely 80 km to the south of the city.